42461-84-7 Flunixin meglumine price CAS 42461-84-7 High Purity

preparation
(1) The 2-chloroenic acid and 2-methyl-3-trifluorothyl amphetamine were mixed into the sodium hydroxide aqueous solution, and the molar ratio of 2-chloroenic acid to 2-methyl-3-trifluoromethyl amphetamine was 3:1; The molar ratio of niacin to sodium hydroxide used in the preparation of sodium hydroxide aqueous solution is 1:2, and the amount of chain polyethyl glycol glycol ether and catalyst A is added to the glycol and catalyst A, and the amount of chain polyethyl glycol glycol ether is 3% of the feed mass of 2-chloroentic acid The catalyst A is for toluene sulfonate and copper oxide, the molar ratio for toluene sulfonate and copper oxide is 3:1; the control temperature is 45 degrees C, after 0.6 hours of reaction, the solution PH is adjusted, after stirring, static layering, after stirring, filtering, washing filter cake, dry fluorine;
(2) The resulting fluonisin and N-methyl glucosamine were reacted in isopropyl alcohol in step 1, and the molar ratio of fluonisin to N-methyl glucosamine was 2:1; the volume ratio of fluonisin to isopropyl alcohol was 1:11; and maltodextrin was added The molar ratio of maltodextrin to 2-methyl-3-trifluoromethyl amphetamine is 1:2.5; heating backflow, filtration, cooling, stirring crystallization, to the system temperature drop below 25 degrees C to continue stirring, crystal filtration by isopropylol washing to obtain fluonisinglumethamphetamine.