Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Fine chemicals, Active pharmaceutical ingredients(APIs), Veterinary, Indole derivatives, Aromatics, Fluorine, Boronic acids, organocatalysts, chiral building blocks, heterocyclic compounds. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.

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Chemwill Asia Co., Ltd.

Country:China (Mainland)

Business Type:Manufacturers

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  • City: Xuzhou
  • Street:High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China
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Indole-3-carbinol CAS 700-06-1 In stock 3-Hydroxymethylindole 3-Indolemethanol Indole-3-methanol

Indole-3-carbinol CAS 700-06-1 In stock 3-Hydroxymethylindole 3-Indolemethanol Indole-3-methanol CAS NO.700-06-1

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Keywords

  • Indole-3-carbinol
  • 3-Hydroxymethylindole
  • 3-Indolemethanol

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  • ProName: Indole-3-carbinol CAS 700-06-1 In ...
  • CasNo: 700-06-1
  • Molecular Formula: CAS 700-06-1
  • Appearance: As per COA
  • Application: It is an important raw material and in...
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  • ProductionCapacity: 5 Metric Ton/Day
  • Purity: high quality
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  • LimitNum: 1 Metric Ton
  • Moisture Content: < 0.5%
  • Impurity: < 0.5%
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Indole-3-carbinol  CAS 700-06-1    In stock  3-Hydroxymethylindole  3-Indolemethanol  Indole-3-methanol

 

700-06-1

CAS 700-06-1

3-Hydroxymethylindole; 3-Indolemethanol; Indole-3-methanol

 

 

 

 

Product Name: Indole-3-carbinol
Synonyms:
Indolemethanol; 3-(Hydroxymethyl)indole; 3-Indolemethanol; 1H-Indol-3-ylmethanol; Indole-3-methanol; 1H-Indole-3-methanol; I3C; AKOS NCG1-0099; 3-Indole methanol; Indo-3-Carbinol
CAS RN.:
700-06-1
EINECS: 211-836-2
Molecular Weight: 147.18
Molecular Formula: C9H9NO
Melting Point(℃): 96-99℃
 
Synonyms 3-Hydroxymethylindole; 3-Indolemethanol; Indole-3-methanol
 
 
Indole-3-carbinol (C9H9NO) is produced by the breakdown of the glucosinolate glucobrassicin, which can be found at relatively high levels in cruciferous vegetables such as broccoli, cabbage, cauliflower, brussels sprouts, collard greens and kale. It is also available in dietary supplements. Indole-3-carbinol is the subject of on-going biomedical research into its possible anticarcinogenic, antioxidant, and anti-atherogenic effects. Research on indole-3-carbinol has been conducted primarily using laboratory animals and cultured cells. Limited and inconclusive human studies have been reported. A recent review of the biomedical research literature found that "evidence of an inverse association between cruciferous vegetable intake and breast or prostate cancer in humans is limited and inconsistent" and "larger randomized controlled trials are needed" to determine if supplemental indole-3-carbinol has health benefits.
Basic Info
Chemical Name indole-3-methanol
Synonyms
INDOLE-3-METHANOL;
3-indolemethanol;
(1H-indole-3-yl)-methanol;
3-INDOLYLMETHANOL;
3-IndoleCarbinol;
Expand
 
CAS No. 700-06-1
Molecular Formula C9H9NO
Molecular Weight 147.17400
PSA 36.02000
LogP 1.66020
Properties
Appearance & Physical State white to off white crystals
Density 1.272 g/cm3
Boiling Point 360.6ºC at 760 mmHg
Melting Point 96-99ºC
Flash Point 171.9ºC
Storage Condition 2-8ºC
Safety Info
RTECS NL9483000
Safety Statements S26-S36
HS Code 2933990090
WGK Germany 3
Risk Statements R36/38
Hazard Codes Xi
 
 
Indole-3-carbinol Basic information
Product Name: Indole-3-carbinol
Synonyms: Indole-3-carbinol,99.5%;Indole-3-carbinol 98%;(1H-Indol-3-yl)-methano;Indol-3-yl-methanol;3-INDOLAMETHANOL;INDOLE-3-CARBINOL:3-INDOLE METHANOL;INDOLE-3-CARBINOL(RG);3-HYDROXYMETHYLINDOLE(INDOLE-3-CARBINOL)
CAS: 700-06-1
MF: C9H9NO
MW: 147.17
EINECS: 211-836-2
Product Categories: blocks;IndolesOxindoles;indole derivative;Indoles and derivatives;IndoleDerivative;Pyrroles & Indoles;Indole;Indoles;Antioxidant;Biochemistry;Simple Indoles;Nutritional Supplements;Aromatics;Heterocycles;-;Halogenated Heterocycles ,Others;pharmaceutical raw material;Inhibitors;Pyrroles & Indoles;Heterocycle-Indole series
Mol File: 700-06-1.mol
Indole-3-carbinol Structure
Indole-3-carbinol Chemical Properties
Melting point 96-99 °C(lit.)
Boiling point 267.28°C (rough estimate)
density 1.1135 (rough estimate)
refractive index 1.5670 (estimate)
storage temp. 2-8°C
form Crystalline Powder or Flakes
color Off-white to yellow-orange
BRN 121323
Stability: 2-80C
InChIKey IVYPNXXAYMYVSP-UHFFFAOYSA-N
CAS DataBase Reference 700-06-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/38
Safety Statements 26-36
WGK Germany 3
RTECS NL9483000
Hazard Note Irritant
HS Code 29339900
MSDS Information
Provider Language
SigmaAldrich English
ACROS English
ALFA English
Indole-3-carbinol Usage And Synthesis
Chemical Properties Off-White Powder
Uses Inhibits cancinogenesis at the initiation stage. A metabolite of 3-methylindole
Uses antineoplastic; inhibitor of Amyloid-beta deposition
Uses nutritional supplement
Definition ChEBI: An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
Anticancer Research I3C is a bioactive compound majorly found in Brassica vegetables including broccoli,cauliflower, and collard greens. I3C and its derivative diindolylmethane (DIM)have been investigated for cancer prevention and treatment of breast, prostate, andovarian cancers. I3C partially modulates the tyrosine kinase/PI3K/Akt signalingpathway which leads to the prevention of lung adenocarcinoma which is induced byusing tobacco carcinogen in A/J mice. DIM transduces signaling via aryl hydrocarbon(Ah) receptor, NF-κB/Wnt/Akt/mTOR signaling pathways, cell cycle arrest,modulated cytochrome P450 enzymes, and altered angiogenetic and invasive,metastatic, and epigenetic behavior of cancer cells. Combination of DIM and I3Cinduces Nrf2-mediated phase II drug metabolizing genes (GSTm2, UGT1A1, andNQO1) and antioxidant genes (HO-1, SOD-1) (Weng et al. 2008; 2012).
Indole-3-carbinol Preparation Products And Raw materials
Raw materials 2,3-DICHLORO-5,8-DIHYDROXY-1,4-NAPHTHOQUINONE

 

 

 

 

Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA. 

Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Basic chemicals , Fine chemicals,  Active pharmaceutical ingredients(APIs), Veterinary,  Indole derivatives, Aromatics, Fluorine, Boronic acids, organocatalysts, chiral building blocks, heterocyclic compounds. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place. 

 

Our R&D team masters core technology for process-design of target building block as well as Tailor-made fine chemicals. Our manufactory specialised in extreme temperature conditions (-100ºC to +300ºC), hydrogenations reaction under high pressure, suzuki coupling reaction, photochemical reaction, Mitsunobu reactions, enantioselective reactions and asymmetric synthesis. 

 

Think Chemistry,Think CHemWill

 

 

Factory Plant Address:
High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China


Shanghai office: (Export Department)
Address: 16FL., INDUSTRY & COMMERCIAL BUILDING, NO.45 YAN’AN ROAD(E), 200002, SHANGHAI, CHINA
 

Ms Mary Chi  -  Sales manager 
 
 
Website: #
 

 

Details

 
 
 
 
Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Basic chemicals , Fine chemicals,  Active pharmaceutical ingredients(APIs), Veterinary,  Indole derivatives, Aromatics, Fluorine, Boronic acids, organocatalysts, chiral building blocks, heterocyclic compounds. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place. 

 

Think Chemistry,Think CHemWill

 

Factory Plant Address:
High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China


Shanghai office: (Export Department)
Address: 16FL., INDUSTRY & COMMERCIAL BUILDING, NO.45 YAN’AN ROAD(E), 200002, SHANGHAI, CHINA
 

Ms Mary Chi  -  Sales manager 
 
 
Website: #
 

 

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Chemwill Asia Co., Ltd.Tel:021-51086038 Fax:021-51861608  Email:chemwillchina@163.com
 Address:High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China,20000