Fexofenadine CAS 83799-24-0 CAS  no 83799-24-0

Fexofenadine

TERFENADINECARBOXYLATE

4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-alpha,alpha-dimethylbenzeneacetic acid

Fexofenadine CAS 83799-24-0 IN Stock 1H-Imidazole CAS 83799-24-0

Fexofenadine COA TDS price MSDS

Fexofenadine MSDS

Product no. chemwill-Fexofenadine-83799-24-0

Fexofenadine Manufacturer High quality Best price In stock factory

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Fexofenadine Chemical Properties
Melting point     218-220°C
Boiling point     697.3±55.0 °C(Predicted)
density     1.171±0.06 g/cm3(Predicted)
storage temp.     Sealed in dry,Store in freezer, under -20°C
solubility     Methanol (Slightly, Heated, Sonicated)
pka    4.43±0.10(Predicted)
form     Solid
color     White to Off-White
Synonyms:    TERFENADINECARBOXYLATE;alpha-dimethyl-tyl)-alph;benzeneaceticacid,4-(1-hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)bu;mdl16455;terfenadineacidmetabolite;2-(4-(1-HYDROXY-4-[4-(HYDROXY-DIPHENYL-METHYL)-PIPERIDIN-1-YL]-BUTYL)-PHENYL)-2-METHYL-PROPIONIC ACID;Fexofenadinebase;FEXOFENADINE(SUBJECTTOPATENTFREE)
CAS:    83799-24-0
MF:    C32H39NO4
MW:    501.66
EINECS:    801-893-7
Fexofenadine
Synonyms        4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-alpha,alpha-dimethylbenzeneacetic acid
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Molecular Structure        CAS # 83799-24-0, Fexofenadine, 4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-alpha,alpha-dimethylbenzeneacetic acid
Molecular Formula        C32H39NO4
Molecular Weight        501.66
CAS Registry Number        83799-24-0
Fexofenadine Usage And Synthesis
Description    Fexofenadine, the carboxylic acid metabolite of terfenadine, is widely available. It accounts for the antihistaminic properties of terfenadine, which is very rapidly metabolized via CYP3A4-catalyzed processes. Members of the organic anion transporter protein family and the drug efflux transporter P-glycoprotein are involved in the disposition of fexofenadine. Fexofenadine does not have the antiarrhythmic side effects of terfenadine.
Chemical Properties    White Powder
Originator    Alernex,Dabur Pharmaceuticals Ltd.,India
Uses    A metabolite of of terfenadine, a H1-Histamine receptor antagonist
Fexofenadine Preparation Products And Raw materials
Raw materials    Magnesium sulfate-->Nitrogen-->Sodium hydride-->Iodomethane-->Triphenylphosphine-->Pentane-->Methanesulfonyl chloride-->TRIMETHOXYCHLOROSILANEDISC 05/06/04-->3-Butyn-1-ol-->Sodium borohydride-->Terfenadine-->4-Piperidinemethanol-->Aluminum chloride-->Iodotrimethylsilane

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block as well as Tailor-made fine chemicals. Our manufactory specialised in extreme temperature conditions (-100oC to +300oC), hydrogenations reaction under high pressure, suzuki coupling reaction, photochemical reaction, Mitsunobu reactions, enantioselective reactions and asymmetric synthesis.we specialize in developing innovative processes for the synthesis of a wide range of products. we also undertake custom synthesis and contract manufacturing. We have Strong quality control system: Strength of our ethical commitment to quality control and quality assurance systems firmly based on ISO standard. QA and QC used in the whole process of raw materal control, process control and finished product quality inspection. Oue company has passed has passed the ISO9001:2008 . Think Chemistry,Think CHemWill.

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Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA.Our main production base is located in Xuzhou industry park.  We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block as well as Tailor-made fine chemicals. Our manufactory specialised in extreme temperature conditions (-100oC to +300oC), hydrogenations reaction under high pressure, suzuki coupling reaction, photochemical reaction, Mitsunobu reactions, enantioselective reactions and asymmetric synthesis.we specialize in developing innovative processes for the synthesis of a wide range of products. we also undertake custom synthesis and contract manufacturing. We have Strong quality control system: Strength of our ethical commitment to quality control and quality assurance systems firmly based on ISO standard. QA and QC used in the whole process of raw materal control, process control and finished product quality inspection. Oue company has passed has passed the ISO9001:2008 .We have flexible payment terms with all of our clients: Various payment terms such as L/C,D/P,D/A and T/T will be accepted. we've been authorized the import&export qualification by the government and also has passed the “iso 9001-2008 quality management system” certification. Our company has strong R&D ability and production experience to provide the customers new APIs. We specialize in developing innovative processes for the synthesis of a wide range of products. We also undertake custom synthesis and contract manufacturing.we always stand on the quality of product as our life, develop in the direction of customers requirement and aim at creating greater value for customers.innovation and honesty, we will make common development with the masses of customers at home and abroad hand in hand by our best service.the aim of qdsigma is a quality policy that "elements in the system all have been satisfied, personnel has been trained; every batch of material is checked, each procedure guarantees the quality; every bag of our products is top grade, service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. the quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services. the aim of qdsigma is a quality policy that "elements in the system all have been satisfied, personnel has been trained; every batch of material is checked, each procedure guarantees the quality; every bag of our products is top grade, service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. the quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.our concept,1.client is first. 2.credibility is the most important.3.quality control is our life.4.great sense of responsibility.5.we will be responsible for not only our products, our clients, also the society.the corporation's slogan：reliable, professional, cooperative and innovative.the corporation's philosophy: widely absorb different excellent views and ideas from all over the world.the corporation's destination: we will constantly strive to supply customers with new and high-tech products and will keep the leadership in the field. Think Chemistry,Think CHemWill.

Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA. 

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place. 

Our R&D team masters core technology for process-design of target building block as well as Tailor-made fine chemicals. Our manufactory specialised in extreme temperature conditions (-100ºC to +300ºC), hydrogenations reaction under high pressure, suzuki coupling reaction, photochemical reaction, Mitsunobu reactions, enantioselective reactions and asymmetric synthesis. 

Think Chemistry,Think CHemWill

Factory Plant Address:
High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China


Shanghai office: (Export Department)
Address: 16FL., INDUSTRY & COMMERCIAL BUILDING, NO.45 YAN’AN ROAD(E), 200002, SHANGHAI, CHINA
 

Ms Mary Chi  -  Sales manager