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Silibinin CAS 22888-70-6  Milk Thistle Extract  IN Stock  Silybin 22888-70-6

22888-70-6 CAS 22888-70-6  highly quality and immedaite delivery  Dimethylbenzenesulfonic acid sodium salt

Silibinin COA TDS price MSDS

Silibinin MSDS

Silibinin TDS

Silibinin price

Product no. chemwill-Silibinin-920923

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Silibinin CAS 22888-70-6

2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin; Silymarin CAS 22888-70-6

Silibinin; Silybin; silymarin group; 2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin; Silybum marianum; Silybum Extract; (2R,3R)-3,5,7-trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-one; (2R,3R)-3,5,7-trihydroxy-2-[(2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-one; Milk Thistle Extract; Milk Thistel P.E.

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Name:    Silymarin

Milk thistle Silybinin and 80%silymarin
80% Silymarin 30% silybin+isosilybin

Name:    Silibinin
Synonyms:    silliver;silybine;silymarinei;silymaringroup;Silymrin;(2R,3R)-3,5,7-TRIHYDROXY-2-[(2R,3R)-3-(4-HYDROXY-3-METHOXY-PHENYL)-2-HYDROXYMETHYL-2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL]-CHROMAN-4-ONE;2-[2R,3R-DIHYDRO-3-(4-HYDROXY-3-METHOXYPHENYL)-2-(HYDROXYMETHYL)-1,4-BENZODIOXIN-6-YL]-2R,3R-DIHYDRO-3,5,7-TRIHYDROXY-4H-1-BENZOPYRAN-4-ONE;2,3-DIHYDRO-3-(4-HYDROXY-3-METHOXYPHENYL)-2-(HYDROXYMETHYL)-6-(3,5,7-TRIHYDROXY-4-OXOBENZOPYRAN-2-YL)BENZODIOXINE
CAS:    22888-70-6
MF:    C25H22O10
MW:    482.44
EINECS:    245-302-5
HS Code     29329990
 Silibinin (INN), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin, and others. Silibinin itself is mixture of two diastereomers, silybin A and silybin B, in approximately equimolar ratio. The mixture exhibits a number of pharmacological effects, particularly in the liver, and there is some clinical evidence for the use of silibinin as a supportive element in alcoholic and child grade 'A' liver cirrhosis.
silliver; Silibinin; SILYBIN A; silybine;
Appearance & Physical State     solid
Density     1.527g/cm3
Boiling Point     793ºC at 760mmHg
Melting Point     164-174ºC
Flash Point     274.5ºC
Refractive Index     1.684
Stability     Stable. Incompatible with strong oxidizing agents, strong bases.
Storage Condition     -20ºC
Vapor Pressure     1.63E-26mmHg at 25°C
Safety Info
RTECS     DJ2981770
Safety Statements     S26-S37/39
HS Code     2932999099
MSDS Information
Silibinin Usage And Synthesis
Chemical Properties    solid
Uses    Labelled Silybin (S465850). Hepatoprotectant.
Definition    ChEBI: A flavonolignan isolated from milk thistle, Silybum marianum, that has been shown to exhibit antioxidant and antineoplastic activities.
Silibinin Preparation Products And Raw materials
Product Categories:    Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical raw material;Plant extracts;chemical reagent;pharmaceutical intermediate;Flavanones;Natural Plant Extract;Angiogenesis InhibitorsCancer Research;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Plant extract;Inhibitors;-;Anti-proliferative AgentsNutrition Research;Angiogenesis;Biochemicals Found in Plants;Bioflavonoids;Cancer Research;Chemopreventive Agents;Aromatics;Chiral Reagents
Mol File:    22888-70-6.mol
Silibinin Structure
Silibinin Chemical Properties
Melting point     164-174°C
alpha     D20 +11° (c = 0.25 in acetone + alcohol)

Product Categories:    intermediate;Pesticides intermediate;FINE Chemical & INTERMEDIATES;Aromatic Aldehydes & Derivatives (substituted);Benzaldehyde;Pyridines ,Halogenated Heterocycles;-;Aldehydes;C7;Carbonyl Compounds
Mol File:    104-88-1.mol
4-Chlorobenzaldehyde Structure
4-Chlorobenzaldehyde Chemical Properties
Melting point     46 °C
Boiling point     213-214℃
density     1.196
vapor density     0.6 (vs air)
vapor pressure     8.75 atm ( 21 °C)
refractive index     1.5550 (estimate)
Fp     52 °F
storage temp.     Store below +30°C.
solubility     935mg/l
form     Liquid
color     White to pale yellow
Water Solubility     935 mg/L (20 ºC)

Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Active pharmaceutical ingredients(APIs), Veterinary, Indole derivatives, Aromatics, Fluorine, Boronic acids, organocatalysts, chiral building blocks, heterocyclic compounds. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block as well as Tailor-made fine chemicals. Our manufactory specialised in extreme temperature conditions (-100oC to +300oC), hydrogenations reaction under high pressure, suzuki coupling reaction, photochemical reaction, Mitsunobu reactions, enantioselective reactions and asymmetric synthesis.we specialize in developing innovative processes for the synthesis of a wide range of products. we also undertake custom synthesis and contract manufacturing. We have Strong quality control system: Strength of our ethical commitment to quality control and quality assurance systems firmly based on ISO standard. QA and QC used in the whole process of raw materal control, process control and finished product quality inspection. Oue company has passed has passed the ISO9001:2008 . Think Chemistry,Think CHemWill.

5) Supply, technological advantages, etc.

Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA.Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Active pharmaceutical ingredients(APIs), Veterinary, Indole derivatives, Aromatics, Fluorine, Boronic acids, organocatalysts, chiral building blocks, heterocyclic compounds. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block as well as Tailor-made fine chemicals. Our manufactory specialised in extreme temperature conditions (-100oC to +300oC), hydrogenations reaction under high pressure, suzuki coupling reaction, photochemical reaction, Mitsunobu reactions, enantioselective reactions and asymmetric synthesis.we specialize in developing innovative processes for the synthesis of a wide range of products. we also undertake custom synthesis and contract manufacturing. We have Strong quality control system: Strength of our ethical commitment to quality control and quality assurance systems firmly based on ISO standard. QA and QC used in the whole process of raw materal control, process control and finished product quality inspection. Oue company has passed has passed the ISO9001:2008 .We have flexible payment terms with all of our clients: Various payment terms such as L/C,D/P,D/A and T/T will be accepted. we've been authorized the import&export qualification by the government and also has passed the “iso 9001-2008 quality management system” certification. Our company has strong R&D ability and production experience to provide the customers new APIs. We specialize in developing innovative processes for the synthesis of a wide range of products. We also undertake custom synthesis and contract manufacturing.we always stand on the quality of product as our life, develop in the direction of customers requirement and aim at creating greater value for customers.innovation and honesty, we will make common development with the masses of customers at home and abroad hand in hand by our best service.the aim of qdsigma is a quality policy that "elements in the system all have been satisfied, personnel has been trained; every batch of material is checked, each procedure guarantees the quality; every bag of our products is top grade, service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. the quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services. the aim of qdsigma is a quality policy that "elements in the system all have been satisfied, personnel has been trained; every batch of material is checked, each procedure guarantees the quality; every bag of our products is top grade, service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. the quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.our concept,1.client is first. 2.credibility is the most important.3.quality control is our life.4.great sense of responsibility.5.we will be responsible for not only our products, our clients, also the society.the corporation's slogan：reliable, professional, cooperative and innovative.the corporation's philosophy: widely absorb different excellent views and ideas from all over the world.the corporation's destination: we will constantly strive to supply customers with new and high-tech products and will keep the leadership in the field. Think Chemistry,Think CHemWill.

Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA. 

Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Basic chemicals , Fine chemicals,  Active pharmaceutical ingredients(APIs), Veterinary,  Indole derivatives, Aromatics, Fluorine, Boronic acids, organocatalysts, chiral building blocks, heterocyclic compounds. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place. 

Our R&D team masters core technology for process-design of target building block as well as Tailor-made fine chemicals. Our manufactory specialised in extreme temperature conditions (-100ºC to +300ºC), hydrogenations reaction under high pressure, suzuki coupling reaction, photochemical reaction, Mitsunobu reactions, enantioselective reactions and asymmetric synthesis. 

Think Chemistry,Think CHemWill

Factory Plant Address:
High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China


Shanghai office: (Export Department)
Address: 16FL., INDUSTRY & COMMERCIAL BUILDING, NO.45 YAN’AN ROAD(E), 200002, SHANGHAI, CHINA