Citicoline sodium CAS 33818-15-4 In stock CAS NO.33818-15-4
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Keywords
- Citicoline sodium
- Citicoline Sodium factory
- CAS 33818-15-4
Quick Details
- ProName: Citicoline sodium CAS 33818-15-4 ...
- CasNo: 33818-15-4
- Molecular Formula: CAS 33818-15-4
- Appearance: As per COA
- Application: It is an important raw material and in...
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- ProductionCapacity: 5 Metric Ton/Day
- Purity: high quality
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- LimitNum: 1 Metric Ton
- Moisture Content: < 0.5%
- Impurity: < 0.5%
- Grade: Industrial Grade
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Citicoline sodium CAS 33818-15-4 In stock
Citicoline Sodium factory
Cytidine 5'-(trihydrogen diphosphate) P'-[2-(trimethylammonio)ethyl] ester inner salt monosodium salt |
English name |
Citicoline Sodium |
|
CAS NO |
33818-15-4 |
|
Formula |
C14H25N4NaO11P2 |
|
Molecular Weight |
510.31 |
|
Appearance |
White powder |
|
Content |
≥99% |
Product Pictures:
5kg/10kg 25kg
|
Clarity |
Clarify |
|
Related substances |
≤0.5% |
|
Packing Specifications |
5kg/barrel,10kg/barrel,25kg/barrel |
|
Certificate |
GMP |
Product Name: | Citicoline sodium |
Synonyms: | CDP-choline-Na, CDP-coline, Citicoline sodium, Cytidine 5μ-diphosphocholine dihydrate sodium salt, Pμ-[2-(Trimethylammonio)ethyl]ester cytidine 5μ-(trihydrogen diphosphate) inner salt monosodium;CDP-choline-Na, CDP-coline, Citicoline sodium, Pμ-[2-(Trimethylammonio)ethyl]ester cytidine 5μ-(trihydrogen diphosphate) inner salt monosodium;Cytidine 5μ-diphosphocholine dihydrate sodium salt;Cytidine 5'-diphosphoric acid α-sodium β-[2-(trimethylammonio)ethyl] ester salt;Cytidine-5'-;Cytidine 5′-diphosphocholine sodium salt dihydrate,CDP-choline-Na, CDP-coline, Citicoline sodium, P′-[2-(Trimethylammonio)-ethyl]-ester cytidine 5′-(tri-hydro-gen di-phos-phate) inner salt monosodium;CITICOLINE SODIUM (CDP-COLINE/ CITIDINE (5I)-DIPHOSPHOCHOLINE);5′-CDP,Na |
CAS: | 33818-15-4 |
MF: | C14H25N4NaO11P2 |
MW: | 510.31 |
EINECS: | 251-689-1 |
Product Categories: | Bases & Related Reagents;Heterocycles;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Phosphorylating and Phosphitylating Agents;-;API;Miscellaneous Natural Products |
Mol File: | 33818-15-4.mol |
Citicoline sodium Chemical Properties |
Melting point | 259-268°C (dec.) |
alpha | D20 +12.5° (c = 1.0 in H2O) |
storage temp. | 2-8°C |
solubility | H2O: 100mg/mL |
form | solid |
color | white |
Water Solubility | Soluble in water (100 mg/ml). |
λmax | 280nm(HCl aq.)(lit.) |
Merck | 13,2343 |
BRN | 4110040 |
InChIKey | YWAFNFGRBBBSPD-OCMLZEEQSA-M |
CAS DataBase Reference | 33818-15-4 |
Citicoline sodium Usage And Synthesis |
Description |
Citicoline is a nucleic acid derivatives, Geiger found that citicoline can restore brain injury in the animal experiments in 1956. Kennedy study confirmed that citicoline can make brain injury recovery in 1957. Takeda pharmaceutical company in Japan developed and produced it in 1961. It was registered in China in 1988, and is currently the best-selling drug among clinical brain diseases. It plays an important role in the synthesis of lecithin, by promoting the synthesis of lecithin and improving brain function. Experiments show that citicoline can enhance the levels of norepinephrine and dopamine in the central nervous system, thereby it can treat cerebrovascular disease, traumatic brain injury and cognitive impairment caused by various reasons, and there are no obvious side effects. Citicoline sodium can enhance the function of brain stem reticular formation, especially the ascending reticular activating system associated with human consciousness; enhance the function of the pyramidal system; inhibit the function of the external system of the cone, and promotes the recovery of the function of the system. For the treatment of sequelae of traumatic brain injury and cerebral vascular accident caused by the nervous system, it can also be used in the treatment of Parkinson's disease, senile dementia has a certain effect; for the treatment of cardiovascular and cerebrovascular diseases; it also have a certain effect for anti-aging, improving learning and memory. |
Application |
|
Chemical Properties | White Solid |
Uses | Naturally occurring nucleotide; intermediate in the major pathway of lecitin biosynthesis. Neuroprotective. It is used in the treatment of ischemic stroke and head trauma. |
Uses | Cytidine 5′-diphosphate (CDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) to produce CTP in support ofDNA and RNA biosynthesis and of ribonucleotide reductase to product dCMP. |
Brand name | CerAxon (Interneuron). |
Citicoline sodium Preparation Products And Raw materials |
Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA.
Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Basic chemicals , Fine chemicals, Active pharmaceutical ingredients(APIs), Veterinary, Indole derivatives, Aromatics, Fluorine, Boronic acids, organocatalysts, chiral building blocks, heterocyclic compounds. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.
Our R&D team masters core technology for process-design of target building block as well as Tailor-made fine chemicals. Our manufactory specialised in extreme temperature conditions (-100ºC to +300ºC), hydrogenations reaction under high pressure, suzuki coupling reaction, photochemical reaction, Mitsunobu reactions, enantioselective reactions and asymmetric synthesis.
Think Chemistry,Think CHemWill
Factory Plant Address:
High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China
Shanghai office: (Export Department)
Address: 16FL., INDUSTRY & COMMERCIAL BUILDING, NO.45 YAN’AN ROAD(E), 200002, SHANGHAI, CHINA
Details
Think Chemistry,Think CHemWill
Factory Plant Address:
High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China
Shanghai office: (Export Department)
Address: 16FL., INDUSTRY & COMMERCIAL BUILDING, NO.45 YAN’AN ROAD(E), 200002, SHANGHAI, CHINA